Mercaptoethanol-resistant human serum antibodies reacting with endotoxin from Neisseria gonorrhoeae.

Mercaptoethanol-resistant human serum antibodies reacting with endotoxin from Neisseria gonorrhoeae.

Sera from fifty patients with gonorrhoea, thirty with non-specific urethritis, and eighty blood donors were treated with mercaptoethanol (ME) and examined by the indirect haemagglutination test for antibodies against endotoxin from gonococci. Erythrocytes sensitized with determinant a of endotoxin from Strains 8551, V, and VII, or determinant b from Strain V were used. The percentage of sera ac...

Human serum antibodies reacting with endotoxin from Neisseria gonorrhoeae.

The chemical composition and serological properties of endotoxin prepared from gonococci by extraction with aqueous ether have been described in previous reports (Maeland, 1969b, 1969c). Aqueous ether endotoxin contains one antigenic determinant of carbohydrate nature (determinant a) and another antigenic determinant of protein nature (determinant b) (Maeland, 1968, 1969a). A serological test s...

Specificity of human serum antibodies against endotoxin from N. gonorrhoeae.

Sera from patients with gonorrhoea were used to study the specificity of human antibodies against determinant a of endotoxin from gonococcal strains 8551, V, and VII. The sera were tested by an indirect haemagglutination technique before and after absorption with endotoxin from the same strains. The sera were used untreated and treated with mercaptoethanol (ME). The untreated and ME-treated ser...

Ciprofloxacin resistant Neisseria gonorrhoeae.

Multidrug-resistant Neisseria gonorrhoeae.